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Hormonal Abnormalities in Patients with Ovulatory Dysfunction are Associated with Changes in Mood States, IV Edition [International Workshop in Neuroendocrinology]

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Author: Serrano F.G., Osorio T., and Vigil P. (2017)



The emotional states and hormones are an interesting field of study, where the changes associated with hormones could be related with possible implications in mental health. Additionally, ovulatory dysfunctions are a single most cause disorder and infertility by changes of sexual hormones levels in women with emotional tension that conduce to a psychosocial stress. Also, recent evidence which implicate the role of hormones and depressive states in patients that use contraceptives open a windows to understand the potential role of hormone as a new field of interest to evaluate possible markers as endocrine disorders and emotional states. However, exist a reduced research of these topics to understand a possible relationship between the role of hormones and their effects in emotional states. Here, we analyzed a data bank of a group of women with ovulatory dysfunction between 13 to 36 years old to evaluate changes in hormonal levels (Prolactin, Follicle-Stimulating Hormone (FSH), Thyroid-Stimulating Hormone (TSH), Estradiol and Testosterone) and a possible association with mood states by the use of 2 psychological test: POMS (Profile of Mood States) which evaluate 6 states: Tension, Depression, Anger, Vigor, Confusion and Fatigue, and as a control the use of FMPS (Frost Multidimensional Perfectionism Scale) which evaluate scales of perfectionism as concert to mistakes, pressure, order, organization, etc. As a result, we found that exist a positive correlation between levels of FSH and tension variable. Also, we found a negative correlation between estradiol with depression that is consistent with recent evidence. Additionally, the normal values considered for a population are not representative to use as a diagnostic, therefore these evidence need to be considered to future investigations. This is the first evaluation in the neuroendocrinology field that correlate moods states with hormonal level dysfunction suggesting potential implications in women health to the future.


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