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Heartache to Happiness: Managing a Six Year Hormonal Subfertility with a Successful Rate of Conception

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By:  Sr. Juliet Macharia, Albert Kihunrwa, Richard Kiritta, Dismas Matovelo, Godfrey Kaizilege, Sr. Clotilda Chuma, Feredina John (18 February 2024)



Background: The inability to conceive is emotionally distressing and
indeed a very painful struggle in which the pain stays with the individual every
day. Hormonal disorders are the leading cause of infertility globally. They do
not only include the hypothalamic pituitary ovarian axis but also the nonereproductive
endocrine glands. Hormonal management helps promote ovum
maturation, which triggers ovulation, increasing the likelihood of conception.

Case presentation:
We report a 36-year-old African lady who presented with an
inability to conceive for six years since marriage and it was associated with an
irregular menstruation cycle length of twenty-four to thirty-six days. She had
anovulatory cycles for seven years, and high Prolactin levels. Her body mass
index was 34.4kg/m2. She had visited several hospitals in and outside Tanzania
without success in conceiving. At Bugando Medical Centre we managed her case
by diet, fertility awareness, and medical management. She conceived after three
months of treatment.

Anovulatory cycles with abnormal bleeding
patterns are a major cause of infertility in reproductive women. Basic hormonal
profiles are essential to confirm where the problem is. Prolactinemia and insulin
resistance affect ovulation. Fertility awareness, lifestyle changes, and medical
management will bring back happiness to most women with subfertility
secondary to hormonal disorders.


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